I'll open this up by admitting I royally messed up. Unfortunately it happened right at the beginning of my build, and I only just found out now that I'm on the "initial startup" phase. 
I wasn't paying attention when assembling my Z motors and accidentally put a 20T pulley on one of the motors, which also means I ended up putting a 16T pulley on my "B" motor. I only found this out now because when I try to home X and Y, the printer doesn't move straight along the axis and pulls slightly to one side. I spent quite a long time examining my configuration, my cable connections, power delivery, etc. only to find that one pulley looked slightly larger on my XY carriage. With that said, that also means that one of my Z axes will also travel at a different rate which will cause all sorts of problems when trying to level the gantry.
I've mitigated this by changing my configuration to match the pulleys that each motor has and that seems to have solved it for now. The gantry moves in straight lines now (or rather, in the intended directions), and the Z axis seems to move up and down evenly.
I'm wondering if anyone has some advice on when I should actually rip everything apart and fix the issue. Should I continue calibrating everything, or should I stop now and correct the issue? I'm not looking forward to the mess it will make pulling everything apart...
PS. In my defence, I had assumed that building a printer and watching TV was a great pairing!
PPS. Writing this has helped me make the decision to fix the issue now, but I figured I've written it so I might as well post it for someone else's benefit.

I wasn't paying attention when assembling my Z motors and accidentally put a 20T pulley on one of the motors, which also means I ended up putting a 16T pulley on my "B" motor. I only found this out now because when I try to home X and Y, the printer doesn't move straight along the axis and pulls slightly to one side. I spent quite a long time examining my configuration, my cable connections, power delivery, etc. only to find that one pulley looked slightly larger on my XY carriage. With that said, that also means that one of my Z axes will also travel at a different rate which will cause all sorts of problems when trying to level the gantry.
I've mitigated this by changing my configuration to match the pulleys that each motor has and that seems to have solved it for now. The gantry moves in straight lines now (or rather, in the intended directions), and the Z axis seems to move up and down evenly.
I'm wondering if anyone has some advice on when I should actually rip everything apart and fix the issue. Should I continue calibrating everything, or should I stop now and correct the issue? I'm not looking forward to the mess it will make pulling everything apart...
PS. In my defence, I had assumed that building a printer and watching TV was a great pairing!
PPS. Writing this has helped me make the decision to fix the issue now, but I figured I've written it so I might as well post it for someone else's benefit.