Based on your question which piqued my interest I took a look at the pico schematic. It appears that there is no port for an SFS v2 so I don't think you can plug it into the pico I'm afraid (though I can be corrected of course). What I'd consider, is maybe investing in a Klipper Expander board and trying that in your pico, perhaps. Another choice might be to scrap the pico and consider something like an SKR mini E3 v3. I'm not quite sure whether that board combined with a klipper expander would work; you'll need to look into that. If you definitely want it to work then an Octopus or Octopus Pro board will be sure to work as I have used both of those on 24 and 48V for my printer in general and they definitely have a port for the SFS.